DNA and Protein Synthesis

Grad Transitions 12, Grade 12

Mitosis has five different stages: interphase, prophase, metaphase, anaphase and telophase. DNA replication occurs during interphase, specifically the synthesis stage of interphase. There are 3 steps involved in DNA replication. Those steps are Initiation, Elongation, and Termination. During initiation, proteins bind to the origin of replication while helicase unwinds the DNA helix and two replication forks are formed at the origin of replication. During elongation, a primer sequence is added with complementary RNA nucleotides, which are then replaced by DNA nucleotides. After elongation is complete, two new double helices have replaced the original helix. Termination requires that the progress of the DNA replication fork must stop or be blocked.

The cell replicates the leading strand as a single piece but replicates the lagging strand in smaller pieces. The leading strand is the strand which is synthesized in the 5′-3′direction while a lagging strand is a strand which is synthesized in the 3′-5′ direction.

 

Novel Study- English 12

English 12, Grade 12

Hidden Figures is a movie about African-American women working at NASA, and how they conquer racism and sexism while working there, and how that leads to a successful space launch.

How did they do it? Why did they continue to fight against this discrimination? They continued to fight against this discrimination because they believed in getting a man into space. They had hope that by being a part of NASA’s history, that it would promote societal change.

This can somewhat answer the question of how does conflict affect people in our society, and it also shows how hope breaks through the conflict, to see a bigger idea and a greater goal in this case.

 

Now getting more into the war aspect of things, is WWII’s surprising secret agent. I really love watching Ted-ed’s and I was watching a playlist they created titled, “Well-Behaved women seldom make history” and I found this video of how Noor Inayat Khan worked with the French resistance to build the network that defeated the Nazi’s.

 

So how does conflict give way to hope?

Great works are performed not by strength but by perseverance.

By dealing with the conflict in a non-violent way, the people from Hidden figures and From Pacifist to spy were able to somewhat or fully overcome their conflicts.

Poetry Analysis- Mansion by NF

English 12, Grade 12

Insidious is blind inception
What’s reality with all these questions?
Feels like I missed my alarm and slept in (slept in)
Broken legs but I chase perfection
These walls are my blank expression
My mind is a home I’m trapped in
And it’s lonely inside this mansion
Yo, my mind is a house with walls covered in lyrics, they’re all over the place
There’s songs in the mirrors written all over the floors, all over the chairs
And you get the uncut version of life when I go downstairs
That’s where I write when I’m in a bad place and need to release
And let out the version of NF you don’t want to see
I put holes in the walls with both of my fists ’til they bleed
You might get a glimpse of how I cope with all this anger in me
Physically abused, now that’s the room that I don’t want to be in
That picture ain’t blurry at all, I just don’t want to see it
And these walls ain’t blank, I just think I don’t want to see ’em
But why not? I’m in here, so I might as well read ’em
I gotta thank you for this anger that I carry around
Wish I could take a match and burn this whole room to the ground
Matter of fact I think I’ma burn this room right now
So now this memory for some reason just won’t come down
You used to put me in the corner, so you could see the fear in my eyes
Then took me downstairs and beat me ’til I screamed and I cried
Congratulations, you’ll always have a room in my mind
But I’ma keep the door shut and lock the lyrics inside
Insidious is blind inception
What’s reality with all these questions?
Feels like I missed my alarm and slept in (slept in)
And slept in
Broken legs but I chase perfection
These walls are my blank expression
My mind is a home I’m trapped in
And it’s lonely inside this mansion
Inside this mansion
Yo my mind is a house with walls covered in pain
See, my problem is I don’t fix things, I just try to repaint
Cover em up, like it never happened
Say I wish I could change, are you confused?
Come upstairs and I’ll show you what I mean
This room’s full of regrets, just keeps getting fuller it seems
The moment I walk in to it is the same moment that I wanna leave
I get sick to my stomach every time I look at these things
But it’s hard to look past when this is the room where I sleep
I look around, one of the worst things I wrote on these walls
Was the moment I realized that I was losing my mom
And one of the first things I wrote was I wish I would have called
But I should just stop now, we ain’t got enough room in this song
And I regret the fact that I struggled trying to find who I am
And I lie to myself and say I do the best that I can
Shrug it off like it ain’t nothing like it’s out of my hands
Then get ticked off whenever I see it affecting my plans
And I regret watching these trust issues eat me alive
And at the rate I’m going they’ll probably still be there when I die
Congratulations, you’ll always have a room in my mind
The question is, will I ever clean the walls off in time?
Insidious is blind inception
What’s reality with all these questions?
Feels like I missed my alarm and slept in (slept in)
And slept in
Broken legs but I chase perfection
These walls are my blank expression
My mind is a home I’m trapped in
And it’s lonely inside this mansion
Inside this mansion
So this part of my house, no one’s been in it for years
I built the safe room and I don’t let no one in there
‘Cause if I do, there’s a chance that they might disappear and not come back
And I admit I am emotionally scared to let anyone inside
So I just leave my doors locked
You might get other doors to open up but this door’s not
‘Cause I don’t want you to have the opportunity to hurt me
And I’ll be the only person that I can blame when you desert me
I’m barricaded inside so stop watching
I’m not coming to the door so stop knocking, stop knocking
I’m trapped here, God keeps saying I’m not locked in
I chose this, I am lost in my own conscience
I know that shutting the wall down ain’t solving the problem
But I didn’t build this house because I thought it would solve ’em
I built it because I thought that it was safer in there
But it’s not, I’m not the only thing that’s living in here
Fear came to my house years ago, I let him in
Maybe that’s the problem ’cause I’ve been dealing with this ever since
I thought that he would leave, but it’s obvious he never did
He must have picked the room and got comfortable and settled in
Now I’m in the position it’s either sit here and let him win
Or put him back outside where he came from, but I never can
‘Cause in order to do that I’d have to open the doors
Is that me or the fear talking?
I don’t know anymore
Lonely (lonely) it’s lonely
Oh yeah, it’s lonely
Inside this mansion
  1. This song/poem is about the writer and his emotional struggles. It addresses his psychological conflict within himself that effects all aspects of his life.
  2. NF is speaking, to himself, and to his fans/audience and giving them insight to his life.
  3. Insidious- proceeding in a gradual, subtle way, but with harmful effects.

Insidious is blind inception- means that he or something else is getting harmed but doesn’t know it until it’s too late.

Is the poem free of cliché’s?

Yes, if anything he is making fun of cliché’s

  • The poem is contemplative about his life
  • Broken legs but I chase perfection
    These walls are my blank expression
    My mind is a home I’m trapped in
    And it’s lonely inside this mansion
  • The first 6 lines of the poem set a sombre tone for the rest of the song
  • The tone does not change within the poem, there is a storyline; however, the tone remains the same
    • There are a lot of end rhymes and internal rhymes, for instance, verse 1

 

A -Insidious is blind inception
A-What’s reality with all these questions?
B-Feels like I missed my alarm and slept in (slept in)
C-Broken legs but I chase perfection
C-These walls are my blank expression
B-My mind is a home I’m trapped in
A-And it’s lonely inside this mansion

  • This is an open poem
    • The whole song is an extended metaphor, for his brain being a mansion.
    • Figurative Language
      1. Metaphors-
        1. These walls are my blank expression
        2. My mind is a home I’m trapped in
        3. And it’s lonely inside this mansion
        4. my mind is a house with walls covered in lyrics, they’re all over the place
        5. There’s songs in the mirrors written all over the floors, all over the chairs
        6. And you get the uncut version of life when I go downstairs
        7. Congratulations, you’ll always have a room in my mind
        8. my mind is a house with walls covered in pain
      2. Imagery-
        1. my mind is a house with walls covered in lyrics, they’re all over the place
          There’s songs in the mirrors written all over the floors, all over the chairs
          And you get the uncut version of life when I go downstairs
        2. So this part of my house, no one’s been in it for years
          I built the safe room and I don’t let no one in there
          ‘Cause if I do, there’s a chance that they might disappear and not come back
          And I admit I am emotionally scared to let anyone inside
          So I just leave my doors locked
          You might get other doors to open up but this door’s not
  • Irony-
    1. I gotta thank you for this anger that I carry around(verbal irony/sarcasm)
    2. Congratulations, you’ll always have a room in my mind (verbal irony/sarcasm)
  1. Title- Mansion is a very accurate and powerful title for this song because the song is comparing a mansion with his mind.

 

  1. Values of the poem
  • The experiences are perfectly recreated within this song through imagery, symbolism, and word choice
  • The experience is intensely felt by the reader
  • The awareness of the topic of mental health and hiding things is sharpened through this song.
  1. Final thoughts-

Mansion is proof that rap can be truly profound. Generally speaking, I am not a fan of rap music; however, NF weaves a story with lyrical precision and passion.