Can we cure all disease? Many people had this question and expected a way to do it, and Various drugs or surgery have been invented. However, Recently, diseases that cannot be cured by drugs or surgery have been discovered. 

Research results that meet such expectations were announced by He Jiankui on November 26, 2018. Genomic editing has succeeded in creating twins that are resistant to AIDS. No method has yet been found to control semi-conservative replication. However, a site-specific nuclease can act on a specific codon combinations using complementary relationships. By using it, it is possible to replicate and incorporate specific sequences by preliminarily blinding the DNAs to be addedand removing only abnormal sequences. In this way, genome editing technology is practical. Diseases caused by genetic abnormalities are approaching resolution. However, genome editing technology have issues.

First, side effects from gene editing were found. Attempting to develop resistance to one disease will lower the tolerance of other diseases. There are also ethical issue because genome editing is performed on fertilized eggs. Therefore, we can’t cure all diseases but we will be able to cure and get resistance to almost disease has high mortality.