self asses- CLE
For this assignment we had to create an obstacle coarse that would show how to complete a task of our choice. We chose to get a marble into a hole as our task. Our coarse went throughout the counter down onto a lower table, and then onto the floor. We had 3 levels of a coarse. Our coarse we started by using a piece of food to bump the piece down the incline to hit jingo pieces until a marble fell through the tunnel. Then it reached the 2nd level which knocked down another row of jenga knocking a marble into a hat which made the folder open up. That knocked over another large row of jenga up another incline to knock a larger marble into the last hole. Once the marble was knocked over that was the end of our task.
We also had 4 energy transformations in our project which were:
Chemical to mechanical
mechanical to mechanical
mechanical to sound
mechanical to gravitational.
3 simple machines:
wheel and axle.
science self assesment
WHAT IS WHOLE GENOME SEQUENCING?
Whole genome sequencing is a process where we can determine the complete DNA sequence of an organism’s genome. To be able to do this you must have a sample of DNA from the organism and it is put into a sequencing machine. After several days the data comes out of the machine as short pieces of DNA sequence called reads. A computer takes these reads and maps them, creating a picture of the individual’s genome. Once the genome picture is assembled, another program looks for differences in the DNA, or variants, that may be causing the medical condition. By allowing the entire genome of a person to be sequenced, every gene can be turned into digital data for analysis.
Genome sequencing technology is continuing to advance as scientists are created more efficient and fast biotechnology to sequence genomes. As it’s cost continues to get cheaper, the rise of the public buying this technology is rising. According to James Lu, in 20 years most people will have the option of having their genomes sequenced. Other scientists have predicted that more consumer genomic data will make its way to practicing physicians. Over the years the price of getting a genome sequences have dropped. Back in 2003 the international human genome sequencing consortium kicked-off the genome analysis by sequencing a complete human genome. It took more than 13 years and cost approximately €2.3B. By 2008, costs had already dropped to less than €1M per genome and last year it was possible to get your genome sequenced for around €900 in a few days. Whole genome sequencing technology is also expanding around the world. A company from the UK called genomics England has made a goal to sequence up to 100,000 whole genomes from patients who carry rare diseases, their families and cancer patients from 11 genomic medicine centres. Several companies such as AstraZeneca, Roche and GSK have signed up to be a part of the gene consortium that gives them access to 5,000 sequenced genomes. France is also part of this advancement of biotechnology through whole genome sequencing. In 2016 they announced the “France medicine genomique 2025” program. This program is aiming to open 12 sequencing centres and ensure 235,000 whole genomes sequences a year.
HOW IS THIS FORM OF BIOTECHNOLOGY USED?
Genome sequencing has many different machines that you can use to sequence. One common was the NovaSeq 6000. The NovaSeq is a machine that provides us with speed and flexibility we need to complete projects more than any other machine. The NovaSeq is supposed to be an easy machine to use and has the data and tools it needs to accumulate information.The MinION is also a machine that weighs under 100 grams but can generate up to 30 GB of DNA sequences, or 7-12 million reads. Because of how simple, and this device is, it has been used in the arctic, and even on the International Space station. WGS provides 3,000 times more information due to the fact that it provides data on all six billion base pairs of the human genome.
How is this form of biotechnology changing the world as we continue to advance towards the future?
With all the biotechnology being formed and brought into the world to advance whole genome sequencing it is very sure that it will not take long until we have very advanced and accurate technology for analyzing genomes and finding cures to such diseases. Whole genome sequencing offers advantages in cancer research, human genetics, environmental research, microbiology, animal research and more. With the biotechnology that already exists WGS (whole genome sequencing) research is finding ways to guide treatments for common cancers and also being used to determine which medications are safe on a person by analyzing their genomes. With WGS scientists will have a better understanding of cancer cells and what genes are mis regulated. This allows scientists to discover what treatment/chemotherapy is best that way patients have less exposure to toxic treatments. The human genome project allows researchers to understand the blueprint of a person. Many people have donated their genomes to further gather information for research. As they learn more about functions of genes and proteins this will have a major impact in the fields of medicine, biotechnology, life sciences and even our lives and how to keep healthy and safe.
Whole Genome Sequencing. (n.d.). Retrieved from https://www.sciencedirect.com/topics/neuroscience/whole-genome-sequencing.
This assignment we used demos as a tool to help us with our equations and seeing how each number fits into the graphing chart. We created a self portrait character that was made up of shapes that we needed. My character looks a little scary, but looks like it has a fun personality which I think represents me well. I used a blue and green outlining because those are my two favourite colours and I tried to make the other colours represent my natural hair and eye colours.
Write up- This assignment we had to create a “self portrait” on demos graphing. This was challenging to figure out, but once you get started you start to see how it works it started to get a lot easier to form what you wanted. While making the portrait I found it most challenging to balance it all and get the sizes to be the exact size and space you want it in. For example, trying to get the hair to reach around your head, and not have it stick out or have it end in different places was one thing I had a lot of challenges with. But once you put in the coordinates of where you wanted to end it seemed to come together. I used different shapes when trying to create a portrait. I used linear, quadric, and circle reactions to create my character. I mostly used lines and circles to put my face together (eyes, brows, nose, mouth etc. ) Overall, this assignment really showed how equations can create many different shapes/lines and how playing around with the numbers made a huge difference in the graphing.
During this lab we had to figure out how tall the flag post was without using a tape measure directly on the pole. We had to measure the distance from the pole to where we stood, our height to eye level, and finally the angle we look up at. All of these calculations would help us figure out a rough height of the pole. We used our knowledge from the lessons we have had on trigonometry.
supplies- Meter stick, tape measure or (trundle wheel), protractor etc.
Question- As humans, would we be able to permanently colonize and live on another planet? What would life look like?
We always hear about how earth is going to end in the near future, and how we won’t have a place to live. But what if we could move and colonize to another planet? Would it be possible? How would we live? Is it safe? How would it affect us? Those are all questions that come to mind when this topic comes up. I have researched to find out if it was possible to colonize on the moon or another planet. But most importantly what would life look like?
Living on the moon-
The moon has a very dusty rough surface, making it not the best place to colonize. Scientists have reported that the moon Is not a “pleasant” place to live compared to earth. The moon has Lunar days and nights, that occurs when the moon is rotating on its axis in line with the sun. The lunar times last 14 days each. The average temperature during the Lunar days would be around 123 degrees Celsius. During Lunar nights it can get as cold as -233 degrees Celsius. Which does not make it suitable for us to be living on. Some parts of the moon have ice, water, and no light during because of how the sun orbits around.
By these facts, it shows that the moon is not the most convenient place to colonize. If we ended up colonizing we would need to have heaters to keep is from freezing, and air conditioners to keep us from over heating. This would take a toll in our daily lives.
Living on Mars-
Unlike other planets, Mars has seasons depending on its axis and where you are located. The southern part of mars, which is away from the sun has very cold winters, and the northern part has very hot summers. The northern part has 7 Months of spring, 6 months of summer, 5 months of fall, 4 months of winter. A year on mars is longer than a year on earth. About a 5-month difference. That means that a day on Mars is over 24 hours, so time is a little off.
Living on mars would be more challenging than living on the moon due to the lack of information on Mars. Mars is a place where we have had very little exploration on, and lack off information. Mars is shown to be a lot more challenging to live on then the moon.
Living in space would be a very challenging time due to needing so much supplies to just survive. As humans we would need a craft or our “homes” to have oxygen for us to breathe that would circulate and keep us alive. We would have to have an oxygen tank while being outside of the craft.
Another thing we would need is food and water. Food and water are another necessity that we would need. Because of science developing you can now take more foods with you. You used to be able to only take freeze-dried food and now you have more varieties.
In conclusion, This question is a tough one, because we will never truly know what life would be like unless we actually travel. My research has shown that earth is a much safer place for humans and wildlife to be living in.
Scientists believe that the moon especially, is a planet that we would be able to one day colonize on. The moon is a place where we could build, develop and live on. But the risks, dangers, and life style is not the best decision in the present. But in the future this could be a possibility. But as of now, we need a lot more research and space exploration.
Video- Will we ever be able to colonize the moon?
My Wonder information Template-