Mutation story
Hi everybody, I’m an LMNA gene, but you can call me Lamin-A. I’m located in the arm of chromosome 1 at position 22 of my host’s body. Usually I create proteins called Lamins, Lamin A and Lamin C. These proteins structural proteins, which means they help create the nuclear envelope, which is responsible for protecting the nucleus so that means I’m pretty important. But when my host was born my gene was mutated and abnormal. My abnormality causes the normal Lamin-A protein to mutate and become Progerin, the gene that causes Progeria.
When my host was born, he looked normal like a healthy baby, but soon he started developing the normal traits of progeria. He experienced growth failure, loss of body fat and hair, aged-looking skin and stiffness of joints. When he grew up, he developed osteoporosis, and cardiovascular disease. Sadly my host will probably die by the age of 14, he does not have much chance of survival.
Questions:
What are the causes of Progeria?
The effects of Progeria
Life span of someone with progeria
How is life affected by progeria?
Why does progeria occur?
Researchers of progeria
Tools I used:
YouTube
Wikipedia
Various health websites
Verifying and citing: I found the same information on multiple different sites so it should be valid info. I also researched the questions individually on different sites
How to process went: I think this process went pretty well