January 2018 archive

Modeling Mitosis Lab

Found below are the stages of Mitosis presented through diagrams in which we used pipecleaners, string and beads to explain our understanding.

Mitosis:

The process of duplicating cells.

Interphase:

The cell is preparing itself for mitosis while DNA is replicating itself.

Prophase:

In this stage (prophase) the chromatids find their match and using a centromere are attached together forming x’s. Attached to the chromosomes are a pink string which represents the growing spindle fibres. The nuclear membrane also disintegrates in this step of mitosis and leaves the remainder of the nuclear contents (which includes the chromosomes) .

Metaphase:

As we mentioned, the nuclear membrane has disintegrated now and the chromosomes are able to move and align in the middle of the cell. Attached to each chromotoide is a spindle fibre which will be useful in the next step.

Anaphase:

The spindle fibres pull the chromosomes apart now making the chromosomes chromatids again. Each chromatid is pulled to the poles (opposite sides) of the cell.

Telophase:

Spindle fibres have now disappeared and the nuclear membrane has reformed in both of the cells. The chromosomes are now encased and are able to relax into chromatin again.

Cytokinesis:

The end result is that I now have two identical and separate cells from the one cell that I started off with.

“The Life of a Genetic Mutation”

Below you can find a video in which I tell a fictional story about a girl named Kate who has Treacher Collins Syndrome. This is considered a genetic mutation and is all explained in the video. I hope you enjoy the fictional storyline and learn something while you’re at it!

Questions I asked during my research:

What is Treacher Collins Syndrome?
Is there a treatment for Treacher Collins Syndrome?
What causes Treacher Collins Syndrome?
How common is Treacher Collins Syndrome?
What and or who does Treacher Collins Syndrome affect?
How can you inherit Treacher Collins Syndrome?
Where does the name “Treacher Collins Syndrome” come from?
How can Treacher Collins Syndrome be diagnosed?

 

As I worked through my research, I used many different tools to answer my questions. Tools such as youtube and different news stations to watch stories of real life Treacher Collins patients along with medical websites and websites from hospitals to help further with my understanding of the topic. By using websites from hospitals I knew that I receiving good information and more importantly, scientific information. Facts was what I needed for my research and not necessarily opinions when I was first learning about the topic. After I had a basic understanding of Treacher Collins Syndrome was when it was nice to watch the real life stories because I was able to follow along with the information being presented.

 

Below I have attached my sources from the medical websites and the real life story video’s:

http://www.seattlechildrens.org/medical-conditions/chromosomal-genetic-conditions/treacher-collins/

https://rarediseases.org/rare-diseases/treacher-collins-syndrome/

(A journey through Treacher Collins Syndrome)

http://abcnews.go.com/US/abc-news-elizabeth-vargas-inspired-boy-treacher-collins/story?id=51205144

https://www.youtube.com/watch?v=feGliiEsomo

(A video explaining Treacher Collins Syndrome)

http://www.dailymail.co.uk/video/news/video-1183728/What-Treacher-Collins-Syndrome.html

 

I believe this project was very successful. I was able to use sites that presented many different facts but were also not to scientifically worded that I couldn’t understand them. For next time I can improve on using even more sources to check my facts and understanding. I believe that the format I presented my video with was a great way to share my understanding and kept the viewers intrigued.