The life of a gene mutation.

Hello. My name is Cella Jr. I am living inside a young girl who living in Africa with the name Asya. She is only 13, but I am a trouble maker. I like to make her life even more difficult than it already is. So when she was born, I came into her body, from both of her of her parents, who were ‘carriers’ back in the good old days. Instead of those ugly round donut-like blood cells, I provide her with a sickle cell in her blood, looking kind of like a crescent moon. From her parents, Asya inherited two abnormal copies of the haemoglobin gene which is me. Then I caused the odd shape of her blood cells. I am causing Asya to have sickle cell disease.

I have a lot of friends like me here in Africa. We are very common here. I also have some relatives out in India, very distant relatives. I am a abnormal Hemoglobin gene located on chromosome 11, that creates the sickle shame of Asya’s blood cell’s. If Asya is ever feels stressed, is dehydrated, in high altitude, or is involved in temperature changes, I can easily cause an attack on her. Most of my attacks cause her blood tubes to be blocked, so not much blood flow can happen. I also cause her to not carry enough oxygen inside her blood cells. My blood cells don’t move easily through her body as well because they are rough, sticky, and of coarse are sickle shaped, just like my families last name. Sickle. I’m Cella Jr Sickle.

I often cause Asya to obtain a lot of pain, from this, and damage to her organs. I know she hates me, but that’s fine, because I am like her bully. I am mean to her, and she can never ignore the pain from me, because I am always there. You could say that I am very rude, and that is very true, so I don’t care about the criticism. I make Asya feel weak and tired, and now she is only expected to live 40 to 60 years.

In her Hemoglobine gene, I will stay, brought here by her mother and father who were both carriers, I will make my hosts life shorter, and cause her a lot of pain in the past, present, and future. I wont be sorry, and never will be, for all the pain that I have caused. From the blockage in her blood stream to the low oxygen levels flowing through her body. I am doing my job very well.

Ask:

In order to complete this assignment, I had to ask some important questions in order to get my answers. When researching, it is important to ask meaning full and knowledgeable questions that can easily lead you in the right direction, and help you find the correct answers that you might be looking for. Some important questions that I started with were, what is sickle cell disease? What causes it? Where does it come from? How is it formed? When all of those answers where completed, and answered as well as I could get, I would then ask more specific questions, for example, what is the Hemoglobin gene? How dose this disease effect the body? What is the life expectancy when you have this disease? And what chromosome is the hemoglobin gene on?

Acquire:

For the backbone of this project, I researched on the internet. However, I did gain lots of my knowledge about sickle cell disease during class from my science teacher Mr. Campbell.

I also watched two youtube video’s

I think that I could have been more accurate with my findings if I didn’t only use the internet to do all of my research. I think that I could have spent more time reading books, or contacting people that actually have sickle cell disease.

Analyze:

When I was investigating sickle cell disease, I started of with writing down information that I already knew about it. We briefly when over this disease in class so I already had some knowledge going into this project. After I wrote down the info that I already knew, I asked other questions that I will need to know for my project, in order to complete it. Once I had enough questions, I researched them online to find out reasonable answers that made sense. Once I had a lot of useful information, I made a story out of it, and used all of my knowledge.

Apply:

When I researched sickle cell disease, I chose websites that where good and official, and watched a youtube video about a girl who actually had sickle cell disease. For most of my websites, I used medical addresses,  that have done a lot of prior research on this disease. Most of the websites I used were written by doctors, of from the government. I also made sure not to use the ones that were adds, or trying to advertise anything in there website.

Asses:

In the beginning of this project, I originally tried to start my story, without doing any research. I went and started to write, and as I found more info, I would add it along the way. After I figured out that this was not the right path to go, I had a good process of collecting my knowledge and writing it down into my story. To do better, I should have given myself a longer timeline to complete this project, and not wait until the last minute.

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