Category Archives: Science 9

Cell Story “The Life of a Cell”: Osteocyte

Part 1: Cell Story

Hello, I am an  osteocyte, and you may not know who I am so let me teach you.  Osteocytes like me are found on all of the bones on your body. Everything like your femur, jawbone, and ribs have tens and thousands of me on them if not millions.

I work with other cells like osteoblasts and osteoclasts to make sure your bone development is on track.  I am one of the three different types of cells that make your bones the way they are.

Now, you may be wondering what I look like. Let’s see this picture taken of me.

File:604 Bone cells.jpg

On the bottom left of the picture, is me. I have long spindly tendrils on the end of me. Unlike the osteoblasts or osteoclasts, I am more slender and smaller than the two.

In order for me to become an osteocyte, I have to develop and mature as an osteoblast. In your bones, there are little pits and holes called ‘lacunas’. If an osteoblast gets trapped inside of this lacuna I will start to form into an osteocyte. While I can form bone to some various degree, my main purpose is to make sure the tissue inside and outside of the bone is in good shape.

The importance of having osteocytes in your body is to make sure that nothing out of the ordinary happens in your bones. Maintaining the tissue in your bone is very important to the health and function of your bones.

Part 2: The Making of the Cell Story

The questions I asked in order to get the information about the osteocytes were:

“What is an osteocyte?”

“Where are osteocytes found?”

“What is the osteocytes purpose?”

“How do osteocytes form?”

“What is the importance of having osteocytes?”

The tools that I used to find this information were:

Gale Engage Learning – Answered the question of what an osteocyte was.

Ebsco Host – Answered the question of where some of the osteocytes can be located.

Google – Answered the question of what the main purpose and function the osteocyte provided and how osteocytes formed as well.

The process I used to investigate this topic was jotting down the information given to me and paraphrasing the information I wrote down as to not plagarise the author of the article.

All of my sources have been cited, and verified as well. Most of my research was spent going through the digital database searching for info. Some had to be done on Google, but it was verified by academic sources.

The process of making this project was very straightfoward and not too hard to follow. With the limited amount of time however, it proved to be quite difficult near the end.

Finding information about osteocytes wasn’t too difficult and the image I used was from the Creative Commons and allowed me to use it in this project.

What I could’ve done better about this project was involve a more broad sense of vocabulary. The vocabulary was meant to be easy to understand, which is good in a sense, but not to my liking.

Another thing I could’ve done to improve this project and later projects to come forth is to spend more time on it. I am unsure whether projects in the school years ahead will have more limited time frames or not, but I must me prepared for it regardless.

Below are my sources cited.

Gale Engage Learning Link:

http://go.galegroup.com/ps/retrieve.do?tabID=Journals&resultListType=RESULT_LIST&searchResultsType=SingleTab&searchType=AdvancedSearchForm&currentPosition=1&docId=GALE%7CA458161408&docType=Report&sort=Relevance&contentSegment=&prodId=SCIC&contentSet=GALE%7CA458161408&searchId=R2&userGroupName=43riss&inPS=true

Google Article Link:

https://www.nature.com/articles/boneres20159#references

EBSCOhost Link:

http://web.b.ebscohost.com/ehost/detail/detail?vid=7&sid=23a2cf63-b6ef-44b7-a0f2-70af6d0e49c9%40sessionmgr101&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#AN=97501109&db=c9h

 

 

Collaboration Fluency

Our project so far was to find out which combination of materials could attract a cork the best. In the video below, I rub a plastic spoon with fur. The result is that t he spoon attracts the cork. When I rub the spoon with fur the electrons from the fur transfers to the spoon. Since the cork is neutral, it will be attracted to the spoon

After the cork has gained electrons and the spoon loses most of its electrons, the spoon will actually repel the cork, showed in the video below.

ebonite Copper Aluminum Straw Glass Wood Lucite spoon
Fur repels attracts attracts Attracts then repels attracts attracts attracts repels
Polyester attracts attracts attracts repels attracts Little attraction Nothing attracts
cotton repels repels Very little attraction attracts attracts Very little attraction Very strong attraction repels
silk attracts attracts attracts  Super Attracts attracts Nothing Very strong attraction repels
Wool attracts Nothing Nothing attracts attracts attracts repels repels
Garbage Bag attracts Nothing attracts attracts Nothing Nothing Nothing Attracts

Many aspects of the collaboration went well. We were able to find information that was able to help us advance to the next step. We had a general idea of what our plan was. Some things that didn’t quite do so well, was the amount of distractions around the room. Others talking to our group off-topic and vice-versa. It was partly my job to put an end to this, but sometimes, a group member is going to do more work than others, and in my case, that’s okay. I was able to make my group take a step back and approach our plan in a different way. Our group was now focused on our task and we ended up with the table above showing how all the materials reacted with the acetate.

One thing that I would do differently or consider is spending more time making sure that my group members were really going to help me on the project. I feel that if I chose different partners, the project would go completely differently. Maybe one or two group members needed a reminder to stay on task, but that shouldn’t have been the case in the first place.

Another thing I would do differently is maybe doing some more research on how to efficiently test how the materials would react to the acetate. Many groups (including mine) didn’t know that they had to zero the acetate/cork and many didn’t ground themselves when testing, remaining on their chairs and leaning their elbows on the table. In the event that I will be testing charges on objects once again, I will remember to take what I’ve learned from this project and apply it to what I would currently be doing.

DEFINE, DISCOVER, DELIVER, and DEBRIEF

Define

Mr. Horton’s son, who has very frequent headaches swore by Advil Liqui Gels for their fastest relief out of many pain relieving medications that he has tried. Our job, as a team of 3-4 was to start brainstorming some ideas on how our experiment would play out. In our groups, we would research on a topic and see what we could find to help us on our experiment. Our experiment was determining which pill out of four dissolved the fastest.The four pills we were testing was an Advil Liqui Gel, Tylenol, Motrin, and a regular Acetaminophen tablet. This experiment’s results will determine whether or not Mr. Horton’s son’s claims are true.

Discover

We had many questions asked during this process, such as

“Which procedure would be the most effective for dissolving the pills?”

Some more questions were asked regarding how we could best simulate the environment of a human stomach such as,

“What liquid will the pills dissolve in?”

“Would the liquid of choice be heated up?”

Other questions were asked,

“What materials will be used in our experiment?”

“What precautions would we have to take for this experiment?”

Our group ended up using a water/hydrochloric acid mixture of about 10ml of water to 5 drops of acid. Our bodies naturally have hyrdrochloric acid in our stomach, so that seemed like a rational thing to add to our experiment. We all decided to not heat up the liquid mixture.

Each pill got its own test tube and would be timed individually. After about 1 minute and 50 seconds have elapsed in our timing process, we would give the test tube 5 taps near the bottom of the tube in hopes of speeding up the process. The timing process would end when the pill had fully dissolved in its test tube.

For precautions, safety was out of the question. Safety gear such as gloves and safety glasses would be used, and one person would be handling the acid as it is an irritant that could make your skin itch and if too many people are handling the equipment, there is an increase chance of some sort of accident happening like a spill,or damaged equipment.

As for materials used, here is our Bill of Materials:

  • 1 Beaker
  • 4 Test Tubes
  • At least 5ml of Hydrochloric acid
  • Timer
  • ~50ml of water
  • Safety gear (Gloves, Goggles)
  • 4 different pain relieving pills

 

Deliver

We were able to retrieve usable data from this experiment. We found that the Tylenol pill was the most effective at dissolving and dissolved in 2:04.66 while, suprisingly, the Advil Liqui Gel never fully dissolved and inevitably took the whole experiment’s time to see a noticeable difference in the shape of the pill, 42:53.77–.

Here are the times of each pill:

Pill  Time to dissolve 
Tylenol 2:04.66
“Ace” 4:58.19
Motrin 5:33.48
Advil 42:53.77–
Advil Liqui Gel being tested.
Tylenol being tested.

Possible safety hazards that were averted were any contact with the acid, confusion and mishandleing of equipment between all group members, and no spillage of any liquids or damaged equipment.

Debrief

Our experiment gave us results, but I don’t think they were the most accurate. The pills tested are meant to be ingested and dissolve in a completely different environment than in cold tap water and hydrochloric acid. While hydrochloric acid is in our stomach, there is more of a cocktail of acids that help break down our food and as our experiment was testing, dissolve pills. Another essential aspect of our experiment, while not necessary, was to find a way to heat up our mixture. Our internal body temperature is about 37° celsius and heating up the mixture would provide an even more realistic environment for our pills to dissolve in. Even enclosing the test tubes or capping them would positively help in our experiment as it would not allow the mixture to be constantly exposed to open, cold air. 

Another event that happened in our experiment was that the Advil Liqui Gel was tested first, and in the end, was the only pill that hadn’t dissolved. This forced us to start testing another pill simultaneously which was not apart of our experiment while it did speed up our procedure. In the event that this experiment is tested once more, testing all the pills simultaneously will be more efficient than testing one by one, as long as each group member keeps an eye on a designated pill looking for any visual queues that the pill had fully dissolved.

Advil Liqui Gel and Acetaminophen tablet being timed, and recorded simultaneously.